Article
Functional Conservation and Genetic Divergence of Chordate Glycinergic Neurotransmission: Insights from Amphioxus Glycine Transporters.
Cells - 2 Dec 2021
Bozzo Matteo, Costa Simone, Obino Valentina, Bachetti Tiziana, Marcenaro Emanuela, Pestarino Mario, Schubert Michael, Candiani Simona
Abstract excerpt
Glycine is an important neurotransmitter in vertebrates, performing both excitatory and inhibitory actions. Synaptic levels of glycine are tightly controlled by the action of two glycine transporters, GlyT1 and GlyT2, located on the surface of glial cells and neurons, respectively. Only limited information is available on glycinergic neurotransmission in invertebrates, and the evolution of glycinergic...
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