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Article

Structure and functions of inhibitory and excitatory glycine receptors.

Annals of the New York Academy of Sciences - 30 Apr 1999

Betz H, Kuhse J, Schmieden V, Laube B, Kirsch J, Harvey R J

Abstract excerpt

The strychnine-sensitive glycine receptor (GlyR) is a pentameric chloride channel protein that exists in several developmentally and regionally regulated isoforms in the CNS. These result from the differential expression of four genes encoding different variants (alpha 1-alpha 4) of the ligand-binding subunit of the GlyR. Their assembly with the structural beta subunit is governed by "assembly cassettes" within...

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PMID: 10414351
DOI: 10.1111/j.1749-6632.1999.tb11343.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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