Article
Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene.
Neuron - 1 May 1993
Borowsky B, Mezey E, Hoffman B J
Abstract excerpt
We have isolated a cDNA encoding a high affinity, Na+/Cl(-)-dependent glycine transporter, GLYT-2, which is distinct from another glycine transporter, GLYT-1. While the 3' sequences of these two cDNAs are identical, the 5' noncoding regions and the N-termini are completely different. GLYT-1 is found only in the white matter of the CNS, while GLYT-2 is found in the gray matter of the CNS as well as in macrophages...
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