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Article

Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice.

Glia - 1 Jul 2010

Eulenburg Volker, Retiounskaia Marina, Papadopoulos Theofilos, Gomeza Jesús, Betz Heinrich

Abstract excerpt

The glycine transporter 1 (GlyT1) is expressed in astrocytes and selected neurons of the mammalian CNS. In newborn mice, GlyT1 is crucial for efficient termination of glycine-mediated inhibitory neurotransmission. Furthermore, GlyT1 has been implicated in the regulation of excitatory N-methyl-D-asparate (NMDA) receptors. To evaluate whether glial and neuronal GlyT1 have distinct roles at inhibitory synapses, we...

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Identifiers

PMID: 20468048
DOI: 10.1002/glia.20987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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