Article
The influence of the -94 Ins/Del ATTG polymorphism of NFkB on the anti-CCP antibody levels in patients with rheumatoid arthritis.
Medicine - 17 Dec 2021
Ayón-Pérez Miriam Fabiola, Topete-Córdoba Jonathan Joseph, Agraz-Cibrián Juan Manuel, Ortiz-Martínez Liliana, Durán-Avelar Ma de Jesús, Vázquez-Reyes Alejandro, Vibanco-Pérez Norberto, Gutiérrez-Franco Jorge, Zambrano-Zaragoza José Francisco
Abstract excerpt
ABSTRACT: Rheumatoid arthritis (RA) is an autoimmune disease characterized by an inflammatory process that affects mainly synovial tissue in joints, and by the production of cyclic citrullinated peptides (anti-CCP) antibodies. In the inflammatory process the regulation of the nuclear factor kappa B (NFkB) transcription factor activation is a key point in the production of inflammatory cytokines. On the other...
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