Article
The -2518 A/G polymorphism in the monocyte chemoattractant protein 1 gene (MCP-1) is associated with an increased risk of rheumatoid arthritis in Argentine patients.
Clinical rheumatology - 1 Dec 2016
Martin Emilia Saint, Schneeberger Emilce E, Aranda Federico M, Peres Silvia Wingeyer, Del Carmen Valerio María, de Los Angeles Correa Maria, Pra Fernando Dal, Martinez Liliana, Remondino Graciela, de Larrañaga Gabriela, Citera Gustavo
Abstract excerpt
The aim of this study was to analyze the influence of nucleotide transition (G/A) in position -2518 of the MCP-1 gene related to the susceptibility of developing RA. Two hundred twenty-three consecutive RA patients according to 2010 ACR/EULAR criteria were included; 120 healthy subjects were used as controls. MCP-1 -2518 A/G polymorphism (AG + GG) was present in 162 (72.6 %) RA patients and in 63 (52.5 %) healthy...
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