Article
STAT4 rs7574865 G/T polymorphism is associated with rheumatoid arthritis and disease activity, but not with anti-CCP antibody levels in a Mexican population.
Clinical rheumatology - 1 Dec 2016
Durán-Avelar Ma de Jesús, Vibanco-Pérez Norberto, Hernández-Pacheco Raquel Rocío, Castro-Zambrano América Del Carmen, Ortiz-Martínez Liliana, Zambrano-Zaragoza José Francisco
Abstract excerpt
Rheumatoid arthritis (RA) is a systemic autoimmune disease in whose etiology genetic factors are known to play an important role. Among the genes associated with RA, STAT4 could be an important factor in conducting helper T cells toward the pro-inflammatory Th1 and Th17 lineages. The aim of this study is to determine the association of the STAT4 polymorphism rs7574865 with RA, disease activity, and anti-cyclic...
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