Article
The TNFA -857C/T Polymorphism: Association with Rheumatoid Arthritis and Anti-CCP Levels in a Mexican Population.
Journal of immunology research - 1 Jan 2019
Agraz-Cibrián Juan Manuel, Espinoza-De León Gabriela Nohemí, Durán-Avelar Ma de Jesús, Vibanco-Pérez Norberto, Ortiz-Martínez Liliana, Vázquez-Reyes Alejandro, Gutiérrez-Franco Jorge, Ayón-Pérez Miriam Fabiola, Zambrano-Zaragoza José Francisco
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic inflammatory disease whose association with SNPs has led to the identification of biomarkers in different populations. To determine the association of the -857C/T SNP of the TNFA gene with RA and clinical parameters, 233 RA patients and 237 healthy controls were included in this study. The -857C/T polymorphism was determined using the TaqMan® system and clinical features...
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