Article
Analysis of the functional <i>NFKB1</i> promoter polymorphism in rheumatoid arthritis and systemic lupus erythematosus
1 Feb 2005
Abstract excerpt
Nuclear factor (NF)-kappaB plays an important role in inflammatory diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). A functional insertion/deletion polymorphism (-94ins/delATTG) has been identified in the promoter of the NFKB1 gene. In addition, a polymorphic dinucleotide repeat (CA) has been identified in proximity to the coding region of the human NFKB1 gene. The aim of the...
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