Article
PADI4 polymorphisms and the functional haplotype are associated with increased rheumatoid arthritis susceptibility: A replication study in a Southern Mexican population.
Human immunology - 1 Sept 2017
Baños-Hernández Christian Johana, Navarro-Zarza José Eduardo, Parra-Rojas Isela, Vázquez-Villamar Mirna, Ramón Padilla-Gutiérrez Jorge, Valle Yeminia, Reyes-Castillo Zyanya, Magdalena Torres-Carrillo Nora, García-Arellano Samuel, Brennan-Bourdon Lorena Michele, Muñoz-Valle José Francisco
Abstract excerpt
Rheumatoid arthritis (RA) is a common autoimmune disease with a complex genetic background. The peptidyl arginine deiminase type IV (PADI4) gene has been associated with RA susceptibility in several populations. We addressed the relationship between three exonic PADI4 gene single nucleotide polymorphisms (SNPs) PADI4_89 (rs11203366), PADI4_90 (rs11203367) and PADI4_92 (rs874881) and related haplotypes with RA in...
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