Article
Identification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombe.
PloS one - 1 Jan 2012
Fujita Ikumi, Tanaka Makiko, Kanoh Junko
Abstract excerpt
The telomere at the end of a linear chromosome plays crucial roles in genome stability. In the fission yeast Schizosaccharomyces pombe, the Rap1 protein, one of the central players at the telomeres, associates with multiple proteins to regulate various telomere functions, such as the maintenance of telomere DNA length, telomere end protection, maintenance of telomere heterochromatin, and telomere clustering in...
Topics
- Binding Sites
- Chromatin
- DNA
- G1 Phase
- Gene Silencing
- Genetic Variation
- Meiosis
- Mutation
- Protein Structure, Tertiary
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins
- Shelterin Complex
- Telomere
- Telomere-Binding Proteins
- Two-Hybrid System Techniques