Article
E2fl1 is a meiosis-specific transcription factor in the protist Tetrahymena thermophila.
Cell cycle (Georgetown, Tex.) - 2 Jan 2017
Zhang Jing, Tian Miao, Yan Guan-Xiong, Shodhan Anura, Miao Wei
Abstract excerpt
Members of the E2F family of transcription factors have been reported to regulate the expression of genes involved in cell cycle control, DNA replication, and DNA repair in multicellular eukaryotes. Here, E2FL1, a meiosis-specific E2F transcription factor gene, was identified in the model ciliate Tetrahymena thermophila. Loss of this gene resulted in meiotic arrest prior to anaphase I. The cytological experiments...
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