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Article

Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.

Molecular biology of the cell - 1 Jan 2002

Katayama Satoshi, Kitamura Kenji, Lehmann Anna, Nikaido Osamu, Toda Takashi

Abstract excerpt

The Skp1-Cullin-1/Cdc53-F-box protein (SCF) ubiquitin ligase plays an important role in various biological processes. In this enzyme complex, a variety of F-box proteins act as receptors that recruit substrates. We have identified a fission yeast gene encoding a novel F-box protein Pof3, which contains, in addition to the F-box, a tetratricopeptide repeat motif in its N terminus and a leucine-rich-repeat motif in...

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Identifiers

PMID: 11809834
DOI: 10.1091/mbc.01-07-0333
PMCID: PMC65083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.PMID 11809834Read ↗

Skp1 and the F-box protein Pof6 are essential for cell separation in fission yeast.Semantic proximity Read ↗

F-box proteins Pof3 and Pof1 regulate Wee1 degradation and mitotic entry in fission yeast.Semantic proximity Read ↗

Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.Semantic proximity Read ↗

14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast.Semantic proximity Read ↗

POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase.Semantic proximity Read ↗

14-3-3 proteins integrate E2F activity with the DNA damage response.Semantic proximity Read ↗

A fission yeast homolog of CDC20/p55CDC/Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2.Semantic proximity Read ↗

SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.Semantic proximity Read ↗

Top3 processes recombination intermediates and modulates checkpoint activity after DNA damage.Semantic proximity Read ↗

Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.Semantic proximity Read ↗

Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.Semantic proximity Read ↗

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