Article
Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms.
European journal of human genetics : EJHG - 1 Jun 2017
van 't Hof Femke Ng, Vaucher Julien, Holmes Michael V, de Wilde Arno, Baas Annette F, Blankensteijn Jan D, Hofman Albert, Kiemeney Lambertus Alm, Rivadeneira Fernando, Uitterlinden André G, Vermeulen Sita H, Rinkel Gabriël Je, de Bakker Paul Iw, Ruigrok Ynte M
Abstract excerpt
Epidemiological studies show that type 2 diabetes (T2D) is inversely associated with intracranial aneurysms (IA) and abdominal aortic aneurysms (AAA). Although adiposity has not been considered a risk factor for IA, there have been inconsistent reports relating adiposity to AAA risk. We assessed whether these observations have a genetic, causal basis. To this end, we extracted genotypes of validated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.