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Gestational diabetes and future cardiovascular diseases: associations by sex-specific genetic data.

European heart journal - 23 Dec 2024

Zhang Yeshen, Yu Shijie, Chen Ziying, Liu Haobin, Li Huixian, Long Xinyang, Ye Fei, Luo Wenzhi, Dai Yining, Tu Shan, Chen Weikun, Kong Siyu, He Yu, Xue Ling, Tan Ning, Liang Huiying, Zhang Zhihui, He Pengcheng, Duan Chongyang, Liu Yuanhui

Abstract excerpt

BACKGROUND AND AIMS: Observational studies have highlighted that gestational diabetes mellitus is associated with a higher risk of cardiovascular diseases, but the causality remains unclear. Herein, the causality between genetic predisposition to gestational diabetes mellitus and the risk of cardiovascular diseases was investigated using sex-specific Mendelian randomization analysis. METHODS: Linkage...

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Cardiovascular Diseases
Coronary Artery Disease
Diabetes, Gestational
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Myocardial Infarction

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PMID: 39453753
DOI: 10.1093/eurheartj/ehae706

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