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Type 2 diabetes has a protective causal association with thoracic aortic aneurysm: a Mendelian randomization study

7 Jun 2023

Abstract excerpt

BACKGROUND: Observational studies have reported an inverse association of type 2 diabetes (T2D) with thoracic aortic aneurysm (TAA). However, the causality of the association has not been established yet. The present study aims to clarify the causal relationship between T2D and TAA via a Mendelian randomization (MR) approach. METHODS: Causality of associations were assessed using a two-sample MR framework....

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PMID: 37280690
DOI: 10.1186/s13098-023-01101-1

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