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Article

CCR5Δ32 mutations do not determine COVID-19 disease course.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Apr 2021

Bernas Stefanie N, Baldauf Henning, Wendler Sarah, Heidenreich Falk, Lange Vinzenz, Hofmann Jan A, Sauter Jürgen, Schmidt Alexander H, Schetelig Johannes

Abstract excerpt

OBJECTIVES: To determine the impact of the 32 bp deletion (CCR5Δ32) in the coding region of the C-C chemokine receptor 5 (CCR5) on the risk of contracting SARS-CoV-2 and severe COVID-19. METHODS: Cross-sectional study among stem cell donors registered with DKMS in Germany. Genetic information was linked to self-reported COVID-19 outcome data. Multivariable regression models were fitted to determine the risk of...

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Identifiers

PMID: 33667698
DOI: 10.1016/j.ijid.2021.02.108
PMCID: PMC7923852

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