Article

The CCR5-delta32 variant might explain part of the association between COVID-19 and the chemokine-receptor gene cluster

2020-11-04

Abstract excerpt

A polymorphism in the LZTFL1 gene located in the chemokine-receptor gene cluster (chromosome 3p) has been associated with the risk of developing COVID-19. The chemokine receptor-5 (CCR5) maps to this region, and the common 32 bp deletion variant (Δ32) has been associated with the extent of inflammatory disease and the outcome in several viral diseases. Several studies have also suggested that the pharmacological t...

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Literature Corpus work: a6101be7-6d1a-57a7-9da6-47e4dd2b46db
DOI: 10.1101/2020.11.02.20224659

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