Article
Distribution of the CCR5 gene 32-bp deletion in Europe.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 1 Oct 1998
Lucotte G, Mercier G
Abstract excerpt
The chemokine receptor CCR5 constitutes the major coreceptor for the macrophage-tropic strains of HIV-1. A mutant allele of the CCR5 gene called delta32 was shown to provide strong resistance to homozygotes against infection by HIV. The frequency of the delta32 allele was investigated in 2522 non...
Topics
- Alleles
- Europe
- Gene Deletion
- Gene Frequency
- Genotype
- Humans
- Receptors, CCR5
