CCR5 deficiency predisposes to fatal outcome in influenza virus infection.

Abstract excerpt

Influenza epidemics affect all age groups, although children, the elderly and those with underlying medical conditions are the most severely affected. Whereas co-morbidities are present in 50% of fatal cases, 25-50% of deaths are in apparently healthy individuals. This suggests underlying genetic determinants that govern infection severity. Although some viral factors that contribute to influenza disease are...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adolescent
• Share to Aged
• Share to Child