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Article

The CCR5-delta32 polymorphism as a model to study host adaptation against infectious diseases and to develop new treatment strategies.

Experimental biology and medicine (Maywood, N.J.) - 1 Aug 2011

Hütter Gero, Ganepola Susanne

Abstract excerpt

Humans respond differently toward exposure against pathogens and some individuals are completely resistant against transmission due to a genetically determined susceptibility. A rising number of such, so-called, host factors have been described during the last years, but their role for diagnostic or therapeutic application is still to be clarified. Here, we describe the biology of the chemokine receptor CCR5 and...

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Source

Identifiers

PMID: 21715437
DOI: 10.1258/ebm.2011.010241

Genes

CCR5

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