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Article

The Role of Topoisomerase II in DNA Repair and Recombination in Arabidopsis thaliana.

International journal of molecular sciences - 4 Dec 2021

Martinez-Garcia Marina, White Charles I, Franklin F Chris H, Sanchez-Moran Eugenio

Abstract excerpt

DNA entanglements and supercoiling arise frequently during normal DNA metabolism. DNA topoisomerases are highly conserved enzymes that resolve the topological problems that these structures create. Topoisomerase II (TOPII) releases topological stress in DNA by removing DNA supercoils through breaking the two DNA strands, passing a DNA duplex through the break and religating the broken strands. TOPII performs key...

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Identifiers

PMID: 34884922
DOI: 10.3390/ijms222313115
PMCID: PMC8658145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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