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Article

Formation of interference-sensitive meiotic cross-overs requires sufficient DNA leading-strand elongation.

Proceedings of the National Academy of Sciences of the United States of America - 6 Oct 2015

Huang Jiyue, Cheng Zhihao, Wang Cong, Hong Yue, Su Hang, Wang Jun, Copenhaver Gregory P, Ma Hong, Wang Yingxiang

Abstract excerpt

Meiosis halves diploid genomes to haploid and is essential for sexual reproduction in eukaryotes. Meiotic recombination ensures physical association of homologs and their subsequent accurate segregation and results in the redistribution of genetic variations among progeny. Most organisms have two classes of cross-overs (COs): interference-sensitive (type I) and -insensitive (type II) COs. DNA synthesis is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26392549
DOI: 10.1073/pnas.1507165112
PMCID: PMC4603498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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