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The role of DNA topoisomerase 1α (AtTOP1α) in regulating arabidopsis meiotic recombination and chromosome segregation.

PeerJ - 1 Jan 2024

Elesawi Ibrahim Eid, Hashem Ahmed M, Yao Li, Maher Mohamed, Hassanin Abdallah A, Abd El-Moneim Diaa, Safhi Fatmah A, Al Aboud Nora M, Alshamrani Salha Mesfer, Shehata Wael F, Chunli Chen

Abstract excerpt

Meiosis is a critical process in sexual reproduction, and errors during this cell division can significantly impact fertility. Successful meiosis relies on the coordinated action of numerous genes involved in DNA replication, strand breaks, and subsequent rejoining. DNA topoisomerase enzymes play a vital role by regulating DNA topology, alleviating tension during replication and transcription. To elucidate the...

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Identifiers

PMID: 39221285
DOI: 10.7717/peerj.17864
PMCID: PMC11365474

Genes

ATM

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