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Grandmaternal smoking during pregnancy is associated with differential DNA methylation in peripheral blood of their grandchildren

28 Mar 2022

Abstract excerpt

The idea that information can be transmitted to subsequent generation(s) by epigenetic means has been studied for decades but remains controversial in humans. Epidemiological studies have established that grandparental exposures are associated with health outcomes in their grandchildren, often with sex-specific effects; however, the mechanism of transmission is still unclear. We conducted Epigenome Wide...

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PMID: 35347270
DOI: 10.1038/s41431-022-01081-2

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