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Article

Arrestin 1 and Cone Arrestin 4 Have Unique Roles in Visual Function in an All-Cone Mouse Retina.

Investigative ophthalmology & visual science - 1 Dec 2015

Deming Janise D, Pak Joseph S, Shin Jung-A, Brown Bruce M, Kim Moon K, Aung Moe H, Lee Eun-Jin, Pardue Machelle T, Craft Cheryl Mae

Abstract excerpt

PURPOSE: Previous studies discovered cone phototransduction shutoff occurs normally for Arr1-/- and Arr4-/-; however, it is defective when both visual arrestins are simultaneously not expressed (Arr1-/-Arr4-/-). We investigated the roles of visual arrestins in an all-cone retina (Nrl-/-) since each arrestin has differential effects on visual function, including ARR1 for normal light adaptation, and ARR4 for...

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Source

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Identifiers

PMID: 26624493
DOI: 10.1167/iovs.15-17832
PMCID: PMC4669854

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ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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