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Substantial restoration of night vision in adult mice with congenital stationary night blindness

21 May 2021

Abstract excerpt

Complete congenital stationary night blindness (cCSNB) due to mutations in TRPM1 , GRM6 , GPR179 , NYX , or leucine-rich repeat immunoglobulin-like transmembrane domain 3 ( LRIT3 ) is an incurable inherited retinal disorder characterized by an ON-bipolar cell (ON-BC) defect. Since the disease is non-degenerative and stable, treatment could theoretically be administrated at any time in life, making it a promising...

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PMID: 34401402
DOI: 10.1016/j.omtm.2021.05.008

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Substantial restoration of night vision in adult mice with congenital stationary night blindnessPMID 34401402Read ↗

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