Article
Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 29 Jun 2016
Berry Justin, Frederiksen Rikard, Yao Yun, Nymark Soile, Chen Jeannie, Cornwall Carter
Abstract excerpt
UNLABELLED: Rhodopsin is a prototypical G-protein-coupled receptor (GPCR) that is activated when its 11-cis-retinal moiety is photoisomerized to all-trans retinal. This step initiates a cascade of reactions by which rods signal changes in light intensity. Like other GPCRs, rhodopsin is deactivated through receptor phosphorylation and arrestin binding. Full recovery of receptor sensitivity is then achieved when...
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