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Article

LAMB2 p.E991K Mutation-Mediated Atherosclerosis in Rabbit.

Genes - 18 Jul 2026

Zhang Ronghan, Mu Chao, Yang Shujun, Jiang Liqiang

Abstract excerpt

Background: Atherosclerosis is a major pathological basis of cardiovascular disease and is influenced by both genetic and environmental factors. Although genome-wide association studies have identified the LAMB2 p.E987K variant as a susceptibility locus for atherosclerosis, its functional role remains unclear. Methods: In this study, a rabbit model carrying the homologous LAMB2 p.E991K mutation was generated...

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Source

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Identifiers

PMID: 42510860
DOI: 10.3390/genes17070820
PMCID: PMC13409397

Genes

LAMB2
CD4
NLRP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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