Article
A Boron Delivery Antibody (BDA) with Boronated Specific Residues: New Perspectives in Boron Neutron Capture Therapy from an In Silico Investigation.
Cells - 18 Nov 2021
Rondina Alessandro, Fossa Paola, Orro Alessandro, Milanesi Luciano, De Palma Antonella, Perico Davide, Mauri Pier Luigi, D'Ursi Pasqualina
Abstract excerpt
Boron Neutron Capture Therapy (BNCT) is a tumor cell-selective radiotherapy based on a nuclear reaction that occurs when the isotope boron-10 (10B) is radiated by low-energy thermal neutrons or epithermal neutrons, triggering a nuclear fission response and enabling a selective administration of irradiation to cells. Hence, we need to create novel delivery agents containing 10B with high tumor selectivity, but...
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