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Tumor Marker–Guided Precision BNCT for CA19-9–Positive Cancers: A New Paradigm in Molecularly Targeted Chemoradiation Therapy

2025-08-29

Abstract excerpt

<title>Abstract</title> <p>Background Boron neutron capture therapy (BNCT) is a molecularly targeted chemoradiation modality that relies on boron delivery agents such as p-borophenylalanine (BPA), which require LAT1 (L-type amino acid transporter 1) for tumor uptake. However, the limited efficacy of BPA in LAT1-low tumors restricts its therapeutic scope. To address this limitation, we developed a tumor marker–gui...

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Literature Corpus work
37af963e-54a0-56a9-b29b-124a9544eca0
DOI
10.21203/rs.3.rs-7314409/v1
Open publication

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Tumor Marker–Guided Precision BNCT for CA19-9–Positive Cancers: A New Paradigm in Molecularly Targeted Chemoradiation TherapyDOI 10.21203/rs.3.rs-7314409/v1
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