Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antibody Conjugates with Unnatural Amino Acids

21 Apr 2015

Abstract excerpt

Antibody conjugates are important in many areas of medicine and biological research, and antibody-drug conjugates (ADCs) are becoming an important next generation class of therapeutics for cancer treatment. Early conjugation technologies relied upon random conjugation to multiple amino acid side chains, resulting in heterogeneous mixtures of labeled antibody. Recent studies, however, strongly support the notion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemical Synthesis and Analysis
Share to HER2/EGFR in Cancer Research
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25898256
DOI: 10.1021/acs.molpharmaceut.5b00082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antibody Conjugates with Unnatural Amino AcidsPMID 25898256Read ↗

High-Throughput Platform to Identify Antibody Conjugation Sites from Antibody-Drug Conjugate Libraries.Semantic proximity Read ↗

Antibody and antibody fragments Site Specific Conjugation using New Q-tag Substrate of Bacterial Transglutaminase.Semantic proximity Read ↗

Affinity‐Directed Site‐Specific Protein Labeling and Its Application to Antibody‐Drug ConjugatesSemantic proximity Read ↗

Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCRSemantic proximity Read ↗

Bispecific antibody conjugates in therapeuticsSemantic proximity Read ↗

Ubi-tagging: A ubiquitin-based modular platform for site-directed antibody conjugationSemantic proximity Read ↗

Expanding the Reach of Monoclonal Antibodies: A Review of Synthetic Nucleic Acid Delivery in ImmunotherapySemantic proximity Read ↗

Antibody Structure and Function: The Basis for Engineering TherapeuticsSemantic proximity Read ↗

Chemically Crosslinked Bispecific Antibodies for Cancer Therapy: Breaking from the Structural Restrictions of the Genetic Fusion Approach.Semantic proximity Read ↗

Engineering of monoclonal antibodies and antibody-based fusion proteins: successes and challenges.Semantic proximity Read ↗

Chemical Diversification of Simple Synthetic AntibodiesSemantic proximity Read ↗

Peptide-Drug Conjugates as Next-Generation Therapeutics: Exploring the Potential and Clinical ProgressSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.