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NR3C1 Glucocorticoid Receptor Gene Polymorphisms Are Associated with Membranous and IgA Nephropathies.

Cells - 16 Nov 2021

Pac Michał, Krata Natalia, Moszczuk Barbara, Wyczałkowska-Tomasik Aleksandra, Kaleta Beata, Foroncewicz Bartosz, Rudnicki Witold, Pączek Leszek, Mucha Krzysztof

Abstract excerpt

Glomerular diseases (GNs) are responsible for approximately 20% of chronic kidney diseases. Glucocorticoid receptor gene (NR3C1) single nucleotide polymorphisms (SNPs) are implicated in differences in predisposition to autoimmunity and steroid sensitivity. The aim of this study was to evaluate the frequency of the NR3C1 SNPs-rs6198, rs41423247 and rs17209237-in 72 IgA nephropathy (IgAN) and 38 membranous...

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Share to Follow-Up Studies
Share to Gene Frequency
Share to Genetic Predisposition to Disease
Share to Glomerular Filtration Rate
Share to Glomerulonephritis, IGA
Share to Glomerulonephritis, Membranous
Share to Polymorphism, Single Nucleotide
Share to Receptors, Glucocorticoid

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Identifiers

PMID: 34831409
DOI: 10.3390/cells10113186
PMCID: PMC8625873

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