Article
Response to prednisone in relation to NR3C1 intron B polymorphisms in childhood nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) - 1 Jul 2008
Zalewski Grzegorz, Wasilewska Anna, Zoch-Zwierz Walentyna, Chyczewski Lech
Abstract excerpt
UNLABELLED: The variation in time required to obtain cessation of proteinuria in children with nephrotic syndrome (NS) represents one aspect of the variations shown by these children in response to glucocorticoid (GC) treatment. Polymorphism of the GC receptor gene (NR3C1) has been postulated as one factor that would partially explain differences in both the clinical presentation and the reaction to treatment in...
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