Article
Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.
The Journal of rheumatology - 1 Jun 2016
Kim Kwangwoo, Bang So-Young, Joo Young Bin, Kim Taehyeung, Lee Hye-Soon, Kang Changwon, Bae Sang-Cheol
Abstract excerpt
OBJECTIVE: Cyclophosphamide (CYC) is an immunosuppressant drug widely used to treat various diseases including lupus nephritis, but its efficacy highly varies from individual to individual. This pharmacogenomics association study searched for genetic variations associated with CYC efficacy. METHODS: Genome-wide association scan was performed for 109 Korean patients with systemic lupus erythematosus with lupus...
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