Article
Association between allelic variants of the human glucocorticoid receptor gene and autoimmune diseases: A systematic review and meta-analysis.
Autoimmunity reviews - 1 May 2018
Herrera Cristian, Marcos Miguel, Carbonell Cristina, Mirón-Canelo José Antonio, Espinosa Gerard, Cervera Ricard, Chamorro Antonio-Javier
Abstract excerpt
INTRODUCTION: The human glucocorticoid receptor gene (NR3C1) is considered to play a role in the differences and sensitivities of the glucocorticoid response in individuals with autoimmune diseases. The objective of this study was to examine by means of a systematic review previous findings regarding allelic variants of NR3C1 in relation to the risk of developing systemic autoimmune diseases. METHODS: Studies...
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