Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of macrophage migration inhibitory factor -173C allele polymorphism with steroid resistance in children with nephrotic syndrome.

Pediatric nephrology (Berlin, Germany) - 1 Nov 2005

Berdeli Afig, Mir Sevgi, Ozkayin Nese, Serdaroglu Erkin, Tabel Yilmaz, Cura Alphan

Abstract excerpt

The potential effects of macrophage migration inhibitory factor (MIF) on the natural immune response are due to the inhibition of immune cell activation, which is regulated by glucocorticoids. In this study, we investigated MIF -173G/C genotype and C allele frequency in 214 patients with idiopathic nephrotic syndrome (INS) and 103 healthy volunteers. We found significant increases in GC genotype (OR=3, p=0.0009)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Glomerulosclerosis, Focal Segmental

Share to Glucocorticoids

Share to Macrophage Migration-Inhibitory Factors

Share to Nephrotic Syndrome

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16133063
DOI: 10.1007/s00467-005-1930-9

Genes

INS
MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of macrophage migration inhibitory factor -173C allele polymorphism with steroid resistance in children with nephrotic syndrome.PMID 16133063Read ↗

Association of the macrophage migration inhibitory factor -173*C allele with childhood nephrotic syndrome.Semantic proximity Read ↗

Macrophage migration inhibitory factor -173G/C gene polymorphism increases the risk of renal disease: a meta-analysis.Semantic proximity Read ↗

A genetic study of steroid-resistant nephrotic syndrome: relationship between polymorphism -173 G to C in the MIF gene and serum level MIF in children.Semantic proximity Read ↗

Polymorphisms of the MDR1 and MIF genes in children with nephrotic syndrome.Semantic proximity Read ↗

Polymorphic variants of MIF gene and prognosis in steroid therapy in children with idiopathic nephrotic syndrome.Semantic proximity Read ↗

NR3C1 Glucocorticoid Receptor Gene Polymorphisms Are Associated with Membranous and IgA Nephropathies.Semantic proximity Read ↗

NR3C1 variants and glucocorticoid response in childhood nephrotic syndrome in North India.Semantic proximity Read ↗

Evidence of association of macrophage migration inhibitory factor gene polymorphisms with systemic lupus erythematosus.Semantic proximity Read ↗

FCGR2A single nucleotide polymorphism confers susceptibility to childhood-onset idiopathic nephrotic syndrome.Semantic proximity Read ↗

Molecular basis of mechanisms of steroid resistance in children with nephrotic syndrome.Semantic proximity Read ↗

Genetic and in vivo determinants of glucocorticoid sensitivity in relation to clinical outcome of childhood nephrotic syndrome.Semantic proximity Read ↗

Relationship between TIM-3 gene polymorphisms and steroid-resistant primary nephrotic syndrome in children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.