Article
NR3C1 gene polymorphisms are associated with steroid resistance in patients with primary nephrotic syndrome.
Pharmacogenomics - 1 Jan 2018
Liu Jie, Wan Zan, Song Qianqian, Li Zhi, He Yijing, Tang Yongjun, Xie Wanying, Xie Yanyun, Zhang Jun
Abstract excerpt
AIM: The aim of this study was to investigate the role of SNPs of genes involved in the glucocorticoid pathway in the development of steroid resistance in patients with primary nephrotic syndrome. METHODS: Sequenom MassARRAY method was used to sequence 25 SNP genotypes in 154 patients. The frequency distribution of the genotypes was compared between patients with steroid-sensitive nephrotic syndrome and those...
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