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Article

CD46 Genetic Variability and HIV-1 Infection Susceptibility.

Cells - 9 Nov 2021

Serrano-Rísquez Carmen, Omar Mohamed, Gómez-Vidal María Amparo, Real Luis Miguel, Pineda Juan Antonio, Rivero Antonio, Rivero-Juárez Antonio, Forthal Donald, Márquez Francisco J, Lo Caputo Sergio, Clerici Mario, Biasin Mara, Caruz Antonio

Abstract excerpt

CD46 is the main receptor for complement protein C3 and plays an important role in adaptive immune responses. CD46 genetic variants are associated with susceptibility to several infectious and autoimmune diseases. Additionally, CD46 function can be subverted by HIV-1 to evade attack by complement, a strategy shared by viruses of other families. We sought to determine the association between CD46 gene variants and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Membrane Cofactor Protein

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 34831317
DOI: 10.3390/cells10113094
PMCID: PMC8622916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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