Article
A genetic variant in the promoter of CD46 is associated with the risk and prognosis of hepatocellular carcinoma.
Molecular carcinogenesis - 1 Nov 2020
Liu Fei, Luo Limei, Liu Zhongjian, Wu Sisi, Zhang Wei, Li Qin, Peng Yufu, Wei Yonggang, Li Bo
Abstract excerpt
CD46 (also known as membrane cofactor protein), which is a member of the membrane-bound complement regulatory protein family, has been reported to cause cancer cells to escape complement-dependent cytotoxicity. However, the association between CD46 polymorphisms and the risk of hepatocellular carcinoma (HCC) has not been investigated. This two-stage association study was conducted to assess the relationship...
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