Article
Association of complement receptor 2 polymorphisms with innate resistance to HIV-1 infection.
Genes and immunity - 1 Mar 2015
Herrero R, Real L M, Rivero-Juárez A, Pineda J A, Camacho Á, Macías J, Laplana M, Konieczny P, Márquez F J, Souto J C, Soria J M, Saulle I, Lo Caputo S, Biasin M, Rivero A, Fibla J, Caruz A
Abstract excerpt
HIV-1 induces activation of complement through the classical and lectin pathways. However, the virus incorporates several membrane-bound or soluble regulators of complement activation (RCA) that inactivate complement. HIV-1 can also use the complement receptors (CRs) for complement-mediated antib...
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