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Article

SuperSelective primer pairs for sensitive detection of rare somatic mutations.

Scientific reports - 17 Nov 2021

Kramer Fred Russell, Vargas Diana Yaneth

Abstract excerpt

SuperSelective primers, by virtue of their unique design, enable the selective exponential amplification of rare DNA fragments containing somatic mutations in the presence of abundant closely related wild-type DNA fragments. However, when a SuperSelective primer is used in conjunction with a conventional reverse primer, linear amplification of the abundant wild-type fragments occurs, and this may lead to a late...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34789731
DOI: 10.1038/s41598-021-00920-4
PMCID: PMC8599793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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