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Article

Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays.

Nature communications - 12 Jul 2022

Chen Lei, Eriksson Anna, Weström Simone, Pandzic Tatjana, Lehmann Sören, Cavelier Lucia, Landegren Ulf

Abstract excerpt

Rare tumor-specific mutations in patient samples serve as excellent markers to monitor the course of malignant disease and responses to therapy in clinical routine, and improved assay techniques are needed for broad adoption. We describe herein a highly sensitive and selective molecule amplification technology - superRCA assays - for rapid and highly specific detection of DNA sequence variants present at very low...

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Share to Acute Myeloid Leukemia Research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35821208
DOI: 10.1038/s41467-022-31397-y
PMCID: PMC9276831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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