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Article

Ultrasensitive Detection of Multidrug-Resistant Mycobacterium tuberculosis Using SuperSelective Primer-Based Real-Time PCR Assays.

International journal of molecular sciences - 12 Dec 2022

Narang Anshika, Marras Salvatore A E, Kurepina Natalia, Chauhan Varsha, Shashkina Elena, Kreiswirth Barry, Varma-Basil Mandira, Vinnard Christopher, Subbian Selvakumar

Abstract excerpt

The emergence of drug-resistant tuberculosis is a significant global health issue. The presence of heteroresistant Mycobacterium tuberculosis is critical to developing fully drug-resistant tuberculosis cases. The currently available molecular techniques may detect one copy of mutant bacterial genomic DNA in the presence of about 1-1000 copies of wild-type M. tuberculosis DNA. To improve the limit of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36555395
DOI: 10.3390/ijms232415752
PMCID: PMC9779475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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