Article
Detection of rare point mutation via allele-specific amplification in emulsion PCR.
BMB reports - 1 May 2013
Cheng Changming, Zhou Yin, Yang Chao, Chen Juan, Wang Jie, Zhang Jie, Zhao Guoping
Abstract excerpt
It is essential to analyze rare mutations in many fields of biomedical research. However, the detection of rare mutations is usually failed due to the interference of predominant wild-type DNA surrounded. Herein we describe a sensitive and facile method of detecting rare point mutation on the basis of allele-specific amplification in emulsion PCR. The identification and selective amplification of rare mutation...
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