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Article

Birth Weight, Cardiometabolic Factors, and Coronary Heart Disease: A Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 18 Oct 2023

Su Shuyao, Fan Jingwen, Yang Yongli, Yang Chaojun, Jia Xiaocan

Abstract excerpt

CONTEXT: Observational studies have shown associations of birth weight (BW) with coronary heart disease (CHD), but results are inconsistent and do not distinguish the fetal or maternal effect of BW. OBJECTIVE: This study aims to explore the causal association between BW and CHD, analyze the fetal and maternal contribution, and quantify mediating effects of cardiometabolic factors. METHODS: Genetic variants from...

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Identifiers

PMID: 37246707
DOI: 10.1210/clinem/dgad308

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