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Fibrinogen β chain and FXIII polymorphisms affect fibrin clot properties in acute pulmonary embolism

16 Nov 2021

Abstract excerpt

Abstract Background Prothrombotic fibrin clot properties, including increased clot density, are in part genetically determined. We investigated whether fibrinogen alpha‐chain gene (FGA) c.991A>G (rs6050), fibrinogen beta chain gene (FGB) −455G>A (rs1800790) and factor XIII gene (F13) c.103G>T (rs5985) polymorphisms affect plasma fibrin clot properties in patients with acute pulmonary embolism (PE). Methods As...

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PMID: 34783023
DOI: 10.1111/eci.13718

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