Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted genetic analysis unveils novel associations between ACE I/D and APO T158C polymorphisms with D-dimer levels in severe COVID-19 patients with pulmonary embolism

13 Nov 2022

Abstract excerpt

Only a percentage of COVID-19 patients develop thrombotic complications. We hypothesized that genetic profiles may explain part of the inter-individual differences. Our goal was to evaluate the genotypic distribution of targeted DNA polymorphisms in COVID-19 patients complicated (PE+) or not (PE-) by pulmonary embolism. We designed a retrospective observational study enrolling N = 94 consecutive patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Cardiovascular Disease and Adiposity
Share to COVID-19 Clinical Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36371754
DOI: 10.1007/s11239-022-02728-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted genetic analysis unveils novel associations between ACE I/D and APO T158C polymorphisms with D-dimer levels in severe COVID-19 patients with pulmonary embolismPMID 36371754Read ↗

ACE Gene I/D Polymorphism and Acute Pulmonary Embolism in COVID19 Pneumonia: A Potential Predisposing RoleSemantic proximity Read ↗

Prognostic Genetic Markers for Thrombosis in COVID-19 Patients: A Focused Analysis on D-Dimer, Homocysteine and ThromboembolismSemantic proximity Read ↗

Association of polymorphisms in genes encoding prothrombotic and cardiovascular risk factors with disease severity in COVID‐19 patients: A pilot studySemantic proximity Read ↗

Genetic and Clinical Determinants of Chronic Thromboembolic Pulmonary Hypertension: The Role of PAI-1 Polymorphism.Semantic proximity Read ↗

Effect of Hereditary Thrombophilia on the Clinical Severity of Covid-19 PneumoniaSemantic proximity Read ↗

Reduction in ACE2 may mediate the prothrombotic phenotype in COVID-19.Semantic proximity Read ↗

Genetic association study of fatal pulmonary embolism.Semantic proximity Read ↗

The ENTPD1 promoter polymorphism -860 A > G (rs3814159) is associated with increased gene transcription, protein expression, CD39/NTPDase1 enzymatic activity, and thromboembolism risk.Semantic proximity Read ↗

Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestrySemantic proximity Read ↗

Molecular Research in Chronic Thromboembolic Pulmonary HypertensionSemantic proximity Read ↗

ACE2 down-regulation may contribute to the increased thrombotic risk in COVID-19.Semantic proximity Read ↗

Thrombophilia genetic mutations and their relation to disease severity among patients with COVID-19.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.