Article
The involvement of blood coagulation factor XIII in fibrinolysis and thrombosis.
Cardiovascular & hematological agents in medicinal chemistry - 1 Jul 2008
Muszbek L, Bagoly Z, Bereczky Z, Katona E
Abstract excerpt
It has been known for a long time that blood coagulation factor XIII (FXIII) is essential for maintaining haemostasis, its deficiency leads to severe bleeding complication. Biochemical studies have revealed that FXIII is a key regulator of fibrinolysis and, in addition to its role in haemostasis, it has also been implicated in the pathology of arterial and venous thrombosis. Most recently, the polymorphisms in...
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