Article
Fibrinogen Aalpha Thr312Ala polymorphism is associated with chronic thromboembolic pulmonary hypertension.
The European respiratory journal - 1 Apr 2008
Suntharalingam J, Goldsmith K, van Marion V, Long L, Treacy C M, Dudbridge F, Toshner M R, Pepke-Zaba J, Eikenboom J C J, Morrell N W
Abstract excerpt
Although chronic thromboembolic pulmonary hypertension (CTEPH) is characterised by the persistence of organised thrombus, few pro-thrombotic risk factors have been identified in subjects with the disease. The aim of the present study was to compare the prevalence of eight functionally relevant haemostatic polymorphisms between CTEPH subjects and healthy controls. Genomic DNA was isolated from 214 CTEPH subjects...
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